lack of association between interleukin-12 gene polymorphisms and recurrent aphthous stomatitis
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Lack of Association between Interleukin-12 Gene Polymorphisms and Recurrent Aphthous Stomatitis
1. Molecular Medicine Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran 2. Dental Research Center, Faculty of Dentistry, Tehran University of Medical Sciences, Tehran, Iran 3. Orthodontic Department, Dental Branch, Islamic Azad University, Tehran, Iran 4. Molecular Immunology Research Center, Tehran University of Medical Sciences, Tehran, Iran 5. Nature of Gene Mutat...
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Recurrent aphthous stomatitis (RAS) is a common oral inflammatory disease with unknown etiology in which the immune system seems to have a role in oral tolerance. Interleukin (IL)-10 is a cytokine synthesis inhibitory factor. Single nucleotide polymorphisms (SNPs) of IL10 gene could alter this cytokine production. The aim of this study was to investigate frequencies of IL10 alleles and genotype...
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Background & Objective: Interleukin (IL)-10 is an important anti-inflammatory and immunomodulatory cytokine. Some authors believe that single nucleotide polymorphisms (SNP) in the promoter region of the IL-10 gene have been associated with susceptibility to HIV infection and progression to AIDS, but its role is not clearly defined yet. The present study was undertaken to evaluate the a...
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background: anxiety-related traits have been attributed to sequence variability in the genes coding for serotonin transmission in the brain. two alleles, termed long (l) and short (s) differing by 44 base pairs, are found in a polymorphism identified in the promoter region of serotonin transporter gene. the presence of the short allele and ss and ls genotypes is found to be associated with the ...
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The aim of this work was to investigate the association between recurrent aphthous stomatitis (RAS) and salivary thiocyanate levels. The sample comprised men and women of age ranging from 15 to 55 years, who were allocated to four groups: 28 patients in RAS active phase (group 1); 28 patients in RAS remission phase (group 2); 29 smokers (group 3); 26 non-smokers without RAS (group 4). Samples o...
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Background Recurrent Aphthous Stomatitis (RAS) is one of the most common diseases of the oral cavity all over the world (5-66%). RAS has a multifactorial etiology, while psychological factors such as stress and anger play a role in its manifestation. The serotonergic mechanisms particularly the serotonin-transporter gene (5-HTT) may affect the risk of psychological alterations and stress respon...
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عنوان ژورنال:
avicenna journal of medical biotechnologyجلد ۸، شماره ۴، صفحات ۲۰۰-۲۰۱
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